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BioNTech SEBullish
BioNTech has entered into a clinical trial collaboration and supply agreement with Gilead Sciences to evaluate the combination of its investigational bispecific immunomodulator, pumitamig, with Gilead’s TROP2-directed ADC, Trodelvy (sacituzumab govitecan). The global Phase 3 ROSETTA Breast-01 trial will be adapted to replace chemotherapy with Trodelvy as a first-line treatment for patients with locally advanced or metastatic PD-L1 low or negative triple-negative breast cancer.…more
BioNTech SE
BioNTech will present 16 abstracts from its late-stage oncology pipeline at the ESMO 2026 Congress, held from October 23 to 27, 2026. Key highlights include initial Phase 2 clinical data for the PD-L1xVEGF-A bispecific immunomodulator pumitamig and results from its novel combination therapies with antibody-drug conjugates (ADCs).…more
BioNTech SE
BioNTech announced that its Phase 2/3 AHEAD-MERIT clinical trial for the mRNA cancer immunotherapy candidate BNT113 failed to meet the dual primary endpoint of progression-free survival (PFS). The trial will continue as planned to evaluate the second dual primary endpoint of overall survival (OS).…more
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BioNTech and BMS Report Positive Phase 2 Data for Lung Cancer Drug Pumitamig…more
BioNTech and Bristol Myers Squibb announced encouraging Phase 2 clinical trial results for their lung cancer candidate, pumitamig, showing improved antitumor activity. As these are early-stage findings, further clinical validation and regulatory approval processes remain necessary.…more
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BioNTech and Gilead Sciences have entered a collaboration to evaluate a combination of pumitamig and sacituzumab govitecan in a Phase 3 trial for triple-negative breast cancer. The partnership aims to adapt the trial to current standards of care to potentially improve patient outcomes.…more
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BioNTech is collaborating with Gilead Sciences to evaluate its investigational drug 'pumitamig' in combination with sacituzumab govitecan for triple-negative breast cancer. While the trial aims to improve treatment standards, the project remains in the clinical development stage without immediate financial impact.…more
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